NUP43 Antibody, Biotin conjugated

Code CSB-PA844045LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NUP43 Polyclonal antibody
Uniprot No.
Target Names
NUP43
Alternative Names
NUP43Nucleoporin Nup43 antibody; Nup107-160 subcomplex subunit Nup43 antibody; p42 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nucleoporin Nup43 protein (1-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
Gene References into Functions
  1. High NUP43 expression was an independent prognostic factor of poor overall survival in luminal A subtype and in HER2+ subtype breast cancer. PMID: 29402145
  2. Data present the crystal structure of full length Nup43 and show that it adopts a canonical WD40 fold similar to other members of the family and interacts with Nup85-Seh1L complex to form a ternary complex. PMID: 26391640
Subcellular Location
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Database Links

HGNC: 21182

OMIM: 608141

KEGG: hsa:348995

STRING: 9606.ENSP00000342262

UniGene: Hs.510375

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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